The assessors will score your answers to questions 2 to 8, question 1 is not scored.
Your answer to each question can be up to 400 words long. Do not include any URLs in your answers unless we have explicitly requested a link to a video.
Question 1. Applicant location (not scored)
You must state the name of your organisation along with your full registered address.
We are collecting this information to understand the geographical location of all participants of a project.
Question 2. Proposed idea or technology
You must provide a description and justification for your proposal and its intended use.
Explain how these have the potential to address the aims of the competition scope.
Describe the current state of development, validation or readiness of your solution. Including its non-clinical, pre-clinical, clinical, manufacturing and regulatory status.
Explain, if necessary, why your project includes animal studies.
You can submit a single appendix as a PDF containing images and diagrams to support your answer. It can be no larger than 10MB and up to 2 A4 pages long. The font must be legible at 100% zoom.
This question will be scored against this assessment criterion: ‘Does the proposal describe a distinct piece of work that will improve the readiness of the vaccine candidate for clinical development or regulatory submission’?
Question 3. Technical project summary
You must provide background to the main technical challenges you are looking to address.
Describe or explain:
- how you will improve the readiness of the vaccine candidate for clinical development or regulatory submission
- what the work package is
- evidence for the scientific and commercial merit of the project based on previous research and development
- the research and development within your proposal that will prove the scientific, environmental and commercial merit of the project
- the main technical deliverables
- what might be achieved on completion of the distinct work package and how it will increase the readiness of the developmental vaccine for future clinical development
This question will be scored against this assessment criterion: ‘How valid is the technical approach?’
Question 4. Project plan and methodology
You must describe your project plan and identify the main milestones.
The plan must be comprehensive. The emphasis throughout should be on practicality. We are seeking evidence that your project will move the vaccine along the development pathway, enhancing its readiness for future clinical development and putting it in a stronger place to obtain future funds.
You must describe or explain:
- what resources will be needed to deliver the project
- what the main success criteria would be
- the main technical, commercial and environmental risks and what you will do to mitigate them
- how you would handle any IP issues which might arise during the project
You must include project management processes that will ensure you achieve the projects milestones. This must show clear evidence that time has been built in to allow for:
- preparation time
- contract out work
- availability and booking of facilities
- any ethical and regulatory approval
If you are working with subcontractors you must explain how you will maintain freedom to operate and fulfil the IP requirements detailed in the contract.
You must upload a project plan or Gantt chart as an appendix in PDF format no larger than 10MB and up to 2 A4 pages. The font must be legible at 100% zoom.
Your milestones must:
- be clear
- be defined using SMART (specific, measurable, achievable, realistic and time-bound) criteria
- be associated with the appropriate deliverables and payments
- indicate your required payment schedule by month
This question will be assessed against these assessment criteria:
‘Does the proposal show a clear plan for completing a distinct piece of work that will advance the vaccine along the developmental pathway and help the readiness of the vaccine candidate for future clinical development and funding opportunities?
Is there a clear management plan?
What are the main technical, commercial and environmental risks to project success?
Will these be effectively managed?
Are the milestones and evaluation procedures appropriate?’
Question 5. Technical team and expertise
Provide a brief description of your technical team.
Include the expertise of each team member or subcontractor that is relevant to your proposal, outlining why they are critical to the project’s success and how much of their time will be spent on the project.
This question will be scored against this assessment criterion: ‘Does the applicant have the skills, capabilities and experience to deliver the intended benefits?’
Question 6. Costs and value for money
How much will the project cost? Demonstrate how the various work items and staff costs are appropriate and represent good value for money.
Describe or explain:
- the total eligible project costs, inclusive of VAT, you are requesting in terms of the project goals
- how this project represents value for money for you and the taxpayer
You can submit a single appendix as a spreadsheet no larger than 10MB and up to 2 A4 pages long to support your answer. The font must be legible at 100% zoom.
Costs quoted must reflect actual costs at a “fair market value” and not include profit.
SBRI is a procurement of R&D services. If successful, you will receive a contract to deliver the proposed activity. You will submit an invoice for the work undertaken.
If you are VAT registered, your total costs are expected to include VAT that you would charge as a service provider. VAT is the responsibility of the invoicing business, and applications are expected to list total costs inclusive of VAT.
If you are not VAT registered, then you must give your costs without VAT. You will not be able to increase invoice values to cover VAT after you have submitted an application.
We cannot provide VAT advice and advise you to seek independent advice for example from HMRC.
Full Economic Cost (FEC) calculations are not relevant for SBRI competitions. SBRI is a competitive process and applications will come from a variety of organisations. Whatever calculation you use to arrive at your total eligible project costs your application will be assessed against applications from other organisations. Bear this in mind when calculating your total eligible project costs. You can include overheads but remember that this is a competitive process.
The assessors are required to judge the application finances in terms of value for money. In other words, does the proposed cost for effort and deliverables reflect a fair market price? They will score your finances against this assessment criterion: ‘Are the budget and costs realistic, justified and appropriate for the aims and methods?’
Please note information from the finances section will be used to support the assessment of this question. Proposed costs stated in this section must match those entered in the finance summary on your application.
Question 7. User or customer engagement
Describe or explain:
- who your potential future users or customers are in low and middle income countries (LMICs)
- how are you working with them to understand their needs and to validate your solution development
This question will be scored against this assessment criterion: ‘How is effective engagement with appropriate potential future users or customers evidenced?’
Question 8. ODA Compliance
This competition is funded from UK Official Development Assistance (ODA). In order to be eligible for ODA funding, the primary purpose of a project must be to benefit the economic development or welfare of one or more countries on the OECD Development Assistance Committee (DAC) list. Projects may have secondary benefits beyond ODA-eligible countries.
Explain why the project is eligible for ODA funding. Describe, with appropriate supporting evidence, what beneficial impact the project is expected to deliver for populations in ODA-eligible countries and over what timescale? What is the pathway to positive impact in ODA-eligible countries after the lifespan of the award?
Your proposal must demonstrate both a high industrial relevance and commercial potential and the potential to produce outputs of health or economic benefit in ODA-eligible countries.
Proposals that do not demonstrate how project outputs are likely to be of primary benefit to populations in ODA-eligible countries will be considered out of scope.
This question will be scored against these assessment criteria: ‘Is there a clear benefit to populations in ODA-eligible countries?